Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs
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چکیده
منابع مشابه
Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs
Platinum drugs continue to be major chemotherapy drugs for cancer treatment. Nevertheless, acquired or intrinsic resistance to these compounds is common in human tumors. One important mechanism for this resistance is the avoidance of cells entering the apoptotic pathway. Nuclear factor-kappa B (NF-kappa B, NF-kappaB) is a pleiotropic transcription factor key in determining the death threshold o...
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ژورنال
عنوان ژورنال: Metal-Based Drugs
سال: 2008
ISSN: 0793-0291,1687-5486
DOI: 10.1155/2008/576104